A Phase II, Double-blind, Randomized, Cross-over Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The purpose of this study is to assess the feasibility of a wearing semiconductor embedded headband for cancer-related cognitive impairment in patients with breast or gynecological cancers. The study will also test the safety and effectiveness of using a semiconductor embedded headband by using a cross-over study design. The study will consist of the following phases: * Phase 1: Participants will be randomly assigned to either receive a headband with an active semiconductor or they will receive a sham headband with no semiconductor. They will wear the assigned headband for 18 hours a day for 3 weeks. * Washout Period: After the first 3-week phase, there will be a 2-week washout period. During this time, participants will not wear either headband to allow time for the potential treatment effects to clear from their body. * Phase 2: After the washout period, participants will switch to the other headband they were previously not receiving. They will wear this assigned headband for 18 hours a day for 3 weeks.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Participant aged 18 years or older.

• Diagnosis of breast or gynecologic cancer.

• Participant has completed chemotherapy within 90 days of enrollment and no additional chemotherapy is planned for the duration of study treatment.

• Perceived cognitive impairment (PCI) score of \< 63 in the FACT-Cog-PCI assessment.

• Ability to wear device for at least 18 hours per day during the 6 weeks of intervention.

• ECOG Performance Status ≤ 3.

• Able to speak and understand English.

• Able to provide informed consent and willing to sign an approved consent form that conforms to federal and institutional guidelines.

Locations
United States
Utah
Huntsman Cancer Institute at University of Utah
RECRUITING
Salt Lake City
Contact Information
Primary
Janna Espinosa
janna.espinosa@hci.utah.edu
8015850571
Backup
Mei Wei, MD
Mei.Wei@hci.utah.edu
801-585-0255
Time Frame
Start Date: 2025-10-09
Estimated Completion Date: 2028-09-30
Participants
Target number of participants: 50
Treatments
Experimental: Semiconductor embedded therapeutic headband
Placebo_comparator: Sham Headband
Related Therapeutic Areas
Sponsors
Leads: University of Utah
Collaborators: INCREDIWEAR HOLDINGS, INC.

This content was sourced from clinicaltrials.gov